On 16/28 October 1893, Tchaikovsky conducted the premiere of his Sixth Symphony,the Pathétique, in Saint Petersburg. Nine days later, Tchaikovsky died there, aged 53.

While Tchaikovsky's death has traditionally been attributed to cholera from drinking unboiled water at a local restaurant, there has been much speculation that his death was suicide.

His inner conflicts, including because of his hidden homosexuality, constantly made him angry. For a long time, there has been a rumor or speculation that the great composer ended his life with arsenic poison.

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